Mitochondrial Protease Profiling

Multi-omic mass spectrometry profiling of 19 single gene deletion yeast strains

Project at-a-Glance


Select a Branch


Datasets
Conditions
Replicates
Measurements
Inter-Replicate Coefficient of Variation (Average)
Measurements Per Replicate (Average)
Measurements Per Condition (Average)
Overlap Between Conditions (Average)

Project Hierarchy


Download Project Materials


Enter Search Term

{{$item.query_term_text}}

Queried Data

Replicate Name Condition Name Set Name Branch Name Molecule Name Molecule Identifier Replicate Quant Value Avg. Quant Value SD Quant Value CV Quant Value All Quant Values Fold Change (Mean Normalized) P-Value (Mean Normalized) FDR-adjusted Q-Value (Mean Normalized) Bonferroni-adjusted P-Value (Mean Normalized) Fold Change (Control Normalized) P-Value (Control Normalized) FDR-adjusted Q-Value (Control Normalized) Bonferroni Adjusted P-Value (Control Normalized)

Outlier Analysis

Figure Legend: Fold changes in {{displayMolecule}} abundance log2(condition/control) versus statistical significance (-log10[p-value]) are shown above. The red data point ({{displayMolecule}} changes in {{displayCondition}}) was identified as a characteristic outlier by the {{algorithm.name}} algorithm.

Datapoints of Interest

Select a Branch

Select an Algorithm

Molecule Name Regulation Condition Distance Fold Change P-Value

Volcano Plot-Full Perturbation Profile {{conditionName}}

{{overflow}}

Select a Branch

Select a Condition






Figure Legend: Fold changes in molecule abundance (condition/control) versus statistical significance (-log10[p-value]).

P < {{pValueCutoff}} and |log2(fold change)| > {{foldChangeCutoff}}

P < {{pValueCutoff}} and |log2(fold change)| < {{foldChangeCutoff}}

P > {{pValueCutoff}}

Fold Changes - {{selectedMolecule.name}}

Select a Branch

Bar Ordering

Select Molecule

{{$item.name}}



Figure Legend: Log2 fold changes in {{selectedMolecule.name}} abundance (log2[condition/control]) are displayed along the x-axis. Error bars represent ±1 standard deviation.

P < {{pValueCutoff}} and |log2(fold change)| > {{foldChangeCutoff}}

P < {{pValueCutoff}} and |log2(fold change)| < {{foldChangeCutoff}}

P > {{pValueCutoff}}

Condition vs Condition Correlation Analysis

Pearson Coefficient: {{pearson | setDecimal:3}} | Slope: {{slope | setDecimal:3}}

Select a Branch

Condition One

Condition Two






Figure Legend: Comparison of fold changes in molecule abundance (log2[condition/control]) for all molecules quantified accross {{condOne.condition_name}} and {{condTwo.condition_name}}. The Pearson coefficient is reported as a metric of profile similarity.

P < {{pValueCutoff}} and |log2(fold change)| > {{foldChangeCutoff}} in both {{condOne.condition_name}} and {{condTwo.condition_name}}.

P < {{pValueCutoff}} and |log2(fold change)| > {{foldChangeCutoff}} in only {{condOne.condition_name}}.

P < {{pValueCutoff}} and |log2(fold change)| > {{foldChangeCutoff}} in only {{condTwo.condition_name}}.

Principal Components Analysis {{"– " +pcaBranch.branch_name}}

Select a Branch

Principal Component (X-Axis)

Principal Component (Y-Axis)



Figure Legend: Principal components analysis (PCA) of all profiled conditions in the '{{pcaBranch.branch_name}}' branch. PCA was performed using averaged log2 fold changes of molecules quantified across all {{condCount}} conditions.

Principal Components Analysis {{"– " +pcaBranch.branch_name}}

Select a Branch

Principal Component (X-Axis)

Principal Component (Y-Axis)



Figure Legend: Principal components analysis (PCA) of all profiled replicates in the '{{pcaBranch.branch_name}}' branch. PCA was performed using log2 abundances of molecules quantified across all {{repCount}} replicates.